Access to healthcare could be drastically changed by the explosive development of mobile health (mHealth) applications, especially in developing nations like India. This study looks into the behavioral elements that affect Indian customers’ acceptance and usage of mHealth apps. Drawing upon established theoretical models such as the Unified Theory of Acceptance and Use of Technology (UTAUT), the research identifies key determinants such as perceived ease of use, perceived usefulness, trust, social influence, health awareness, and privacy concerns. A mixed-method approach was used to collect data from a wide sample of Indian urban customers, combining quantitative surveys and qualitative interviews. The results would emphasize how perceived utility and trust have a big influence on adoption, whereas privacy worries and low digital literacy serve as obstacles. The cultural dynamics specific to India were reflected in the mediating components that emerged: social influence and health awareness. To increase mHealth acceptance and maximize its advantages for a larger population, the study offers practical suggestions for app developers, legislators, and healthcare providers.