The integration of Augmented Reality (AR), Virtual Reality (VR), and the Metaverse in the Learning Ecosystem represents an innovative approach to enhance educational opportunities, emotional well-being, and overall success for students with special needs. This study introduces the Adaptive Metaverse Learning Ecosystem (AMLE), a novel model designed to address accessibility challenges, sensory sensitivities, and personalized learning for a diverse range of disabilities. Students can create unique avatars within the AMLE, fostering natural engagement in online classrooms. Real-time monitoring of students’ attention and attitudes provides valuable insights for educators and parents. Cognitive Accessibility Analysis exhibits an impressive compatibility of 96.8% with AMLE, showcasing its effectiveness in accommodating diverse cognitive profiles. When compared with traditional AR-VR approaches, Cognitive Accessibility Analysis demonstrates a high correlation of 94.2%, emphasizing the advancements offered by AMLE in cognitive accessibility. Social Interaction Analysis reveals a remarkable compatibility of 96.2% with AMLE, highlighting its prowess in fostering social engagement and collaboration among students. In contrast, the correlation with AR-VR stands at 89.7%, underscoring the superiority of AMLE in promoting meaningful social interactions.