Titania nanotubes are one of the most essential and practical compounds in materials science that have many applications in the production of catalytic materials, gas sensors, biomedical devices, solar cells etc. In this article, the graph of Titania nanotubes is investigated. By providing a method to obtain the degree of vertices in the section of the corresponding nanotube, the topological indices of Revan and its Hyper Revan are calculated. Next, the Revan and Hyper Revan indices in line graph of Titania nanotubes are also computing. To compare the obtained values, diagrams of Revan and Hyper Revan indices are drawn.