Makherjee and Park [1] introduced and studied a notion for a fuzzy soft bitopological space. This article introduce notions for fuzzy soft pre-open (closed) set of fuzzy soft bitopological space and studied their basic properties. we use these notions to characterize fundamental concepts of fuzzy soft bitopological spaces such as fuzzy soft pre-closures and fuzzy soft pre-interior of a fuzzy soft bitopological space and prove some of their axioms. Through the use of a notion for soft quasi coincidence, as well as we characterized the concept for a fuzzy soft quasi pre-separation axioms of bitopological space pre- Ti (i = 0, 1, 2) of bitopological space and prove some theorems related to the relation between them.