The article considers the urgent problem of ensuring the security of big data transmitted from aircraft in the context of rapid development of information technologies. A new approach to cryptographic protection of information using blockchain technology is proposed, which allows to increase the efficiency of existing systems. The advantages of using blockchain to guarantee the integrity, confidentiality and availability of data transmitted from unmanned aerial vehicles (UAVs) are analyzed. Particular attention is paid to the possibilities of integrating cryptographic algorithms with blockchain into UAV data management systems. The article also presents methods for effective encryption and decentralized data processing in order to ensure reliable protection of information from unauthorized access and modification.